Investigation of the antimicrobial activities of solvent extracts of two endemic species from Turkey: Campanula tomentosa Lam. and Verbascum mykales Bornm.

Background and Aims: Campanula tomentosa Lam. Verbascum mykales Bornm. are endemic species in Turkey. Extracts of these plants contain important natural compounds such as flavonoids, saponins tannins. This study investigates the antimicrobial effects leaf extracts C. V. against some bacteria yeasts. Materials Methods: Leaves plant samples were air-dried ground into powder. Five solvents (ethyl acetate, methanol, acetone, chloroform, boiled water) used for extraction. Experiments conducted using crude on seventeen bacteria, three yeasts microfungi. The agar well diffusion method was activities extracts. In addition, minimum inhibitory concentrations, bacteriocidal concentration, minimal fungicidal concentrations carried out. Results: ethyl acetate methanol found to be highly effective tested microorganisms. According MIC values, had a strong effect (4-8 ?g/mL) Escherichia coli ATCC 35218, Micrococcus luteus 9341, Streptococcus pneumonia 27336, Pseudomonas aeruginosa 35032, Mycobacterium smegmatis 607, Proteus vulgaris 33420, Enterococcus faecalis 29212, Bacillus cereus 11778, subtilis 6633. extract moderate (64 Candida albicans 10231 Saccharomyces cerevisiae 9763, Aspergillus flavus 9807 niger 16404. However, water no Conclusion: their being investigated first time. both most Gram (+) (-) bacteria. all have fewer microfungi. demonstrates that more prokaryotic microorganisms than eukaryotes.